Annie was interested in becoming a painter, having earned her mother's artistic side. She was a quite, shy girl, as described by her brother. When her mother died of cancer, Annie took responsibility for the family. She would work two jobs at a time to earn money for them. But after a few years of Shifting she started to regress. Annie stopped caring for things like painting, and would only want to sleep and eat. She began to be more animal-like, not being the protective sister that Rafe knew.It is known that this is a common side affect of the skin-walkers, affecting Maya as well.
When Annie moved to Salmon Creek with her brother, they lived in a cabin that they 'inherited'. She meets Samantha Russo when her brother reveals that he thinks she is the skin-walker their mother told them about. Sam is upset with Annie, who is obviously mentally challenged, and lashes out at her in annoyance. Rafe finds them and gets mad at Sam, acting cold towards her whenever they meet. Some time later, when Rafe suspects that Maya is in fact the skin-walker, Annie goes to meet her at the school too. Maya acts much nicer to her than Sam, and reveals to Rafe that she wanted to introduce her to the others in Salmon Creek. When Annie finds Rafe and Maya kissing in a tree she climbs up to talk to them. After she jumps down, Rafe tells her to be careful in case she makes Maya fall, but Annie just says that she would "land on her feet, just like me" referring to their feline ancestry.
Once she is captured by the Nasts, they help her to work through her regression,with her claiming that she got about "20 good minutes a day" with the medicine they were giving her. Annie gets to meet Maya 'herself' and tells her that she is happy that her brother has someone like her. Maya remarks that Annie is still the girl she met before, but more composed, her hugs still kind but not the fierce ones she greeted Maya with before. During the evacuation Annie suspects that Maya and her brother will be escaping in the van and asks the guards if she can switch with Hayley as she doesn't think she is meant to be with them in that van. When her brother tries to talk to her she assures him that she has a doctor in the other van who will be able to help her. Annie is later reunited with Rafeal and they live together in a cabin in Badger Lake.